UM researchers have developed a deep learning model to predict compound protein interactions. GraphBAN is an inductive graph-based approach. The model is all about discovering new drug candidates in the pre-clinical stage. This means speeding up the drug
阅读全文For years scientists have puzzled over why the intracellular pathogen Salmonella is able to survive—and thrive—in human and animal tissues, even within otherwise hostile cells that are part of the body's immune system, such as white blood cells known as
阅读全文Last week, Colossal Biosciences made global headlines when they announced that they had successfully brought the dire wolf back from extinction, or at least a version of one. Colossal's team used pieces of the genetic code they uncovered in ancient dire
阅读全文Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.
阅读全文Industrial farming practices often deplete the soil of important nutrients and minerals, leaving farmers to rely on artificial fertilizers to support plant growth. In fact, fertilizer use has more than quadrupled since the 1960s, but this comes with serio
阅读全文Farmers in dozens of countries have embraced crops genetically engineered to produce proteins from Bacillus thuringiensis (Bt) bacteria that kill some key pests yet are safe for people and wildlife. Although this biotech approach reduces reliance on insec
阅读全文If you think doomscrolling leads to sleepless nights, imagine waking up in bed with a blood-sucking monster the size of a basset hound. That's the waking nightmare one species of Australian fruit fly must contend with each night as hungry mites stalk and
阅读全文Pathogenic Salmonella injects effector proteins into the cells of the gastrointestinal tract to penetrate and multiply within them. The bacteria are usually ingested with contaminated food. They can cause serious gastrointestinal inflammation and even sys
阅读全文The topsoil organic carbon pool is at high risk in 43 to 83 million hectares of EU and UK agricultural land, primarily in cool and humid regions, according to a JRC-led study published in Nature Communications. This corresponds to 23% to 44% of all EU+UK
阅读全文Researchers have discovered a type of "molecular glue" that can be used to inhibit certain pathological protein interactions. Their findings were published in the paper, "Molecular glues that inhibit deubiquitylase activity and inflammatory
阅读全文Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of prota
阅读全文A trio of animal physiologists at the University of Tübingen, in Germany, has found that at least one species of crow has the ability to recognize geometric regularity. In their study published in the journal Science Advances, Philipp Schmidbauer, Madita
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